Preliminary Evaluation of Potential Disease Modification by Hylan G-F 20 (Synvisc®) Using dGEMRIC
نویسندگان
چکیده
INTRODUCTION Treatment of osteoarthritis (OA) continues to be primarily based on symptom modification. The concept of disease modification for OA has been proposed and potential drugs are in the pipeline. Hylan G-F 20 (Synvisc) is an FDA-approved hyaluronate derivative which is administered by injection into osteoarthritic joints for treating pain associated with osteoarthritis. The present study was designed to determine if dGEMRIC imaging could detect cartilage changes over time in patients being treated with Hylan G-F 20 therapy.
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